This page highlights some of our published work. For the complete list of publications from the Kobow Lab, please refer to PubMed or Google Scholar.
- Human brain tissue with MOGHE carrying somatic SLC35A2 variants reveal aberrant protein expression and protein loss in the white matter. Acta Neuropathol 2025. PMID: 40042641
- Analysis of 1386 epileptogenic brain lesions reveals association with DYRK1A and EGFR. Nature Commun 2024. PMID: 39616148
- Deep histopathology genotype-phenotype analysis of focal cortical dysplasia type II differentiates between the GATOR1-altered autophagocytic subtype IIa and MTOR-altered migration deficient subtype IIb. Acta Neuropathol Commun 2023. PMID: 37946310
- Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment. Nature Commun 2023. PMID: 37884489
- The specific DNA methylation landscape in focal cortical dysplasia ILAE type 3D. Acta Neuropathol Commun 2023. PMID: 37278968
- D-galactose Supplementation for the Treatment of MOGHE: A Pilot Trial of Precision Medicine After Epilepsy Surgery. Neurotherapeutics 2023. PMID: 37278968
- Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes. Acta Neuropathol 2023. PMID: 36973520
- DNA methylation-based classification of malformations of cortical development in the human brain. Acta Neuropathol 2022. PMID: 34797422
- Epigenetic genes and epilepsy – emerging mechanisms and clinical applications. Nat Rev Neurol 2022. PMID: 35859062
- The genomic landscape across 474 surgically accessible epileptogenic human brain lesions. Brain 2022. PMID: 36226386
- The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission. Epilepsia 2022. PMID: 35706131
- Experimental Epileptogenesis in a Cell Culture Model of Primary Neurons from Rat Brain: A Temporal Multi-Scale Study. Cells 2021. PMID: 34831225
- Neocortical development and epilepsy: insights from focal cortical dysplasia and brain tumours. Lancet Neurol 2021. PMID: 34687638
- Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE). Acta Neuropathol Commun 2021. PMID: 33407896
- Mosaic trisomy of chromosome 1q in human brain tissue associates with unilateral polymicrogyria, very early-onset focal epilepsy, and severe developmental delay. Acta Neuropathol 2020. PMID: 32979071
The Kobow Lab
Universitätsklinikum Erlangen
Dept. of Neuropathology
Schwabachanlage 6
91054 Erlangen, Germany
katja.kobow@uk-erlangen.de
+49 (09131) 85-34782
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The Kobow Lab 